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Research

We are growing! Every year, HTRIC is funding four PhD projects. The projects are powered by principal investigators from the Faculty of Science and Engineering (FSE) of the University of Groningen of the Hanze University of Applied Sciences, and the University Medical Center Groningen (UMCG). Interested in these projects? Find out more information in the blogs of our candidates.

Oxygen-releasing adhesives to promote anastomotic healing in esophageal surgery

PhD candidate Mariana Leal Estrada

After finishing my bachelor’s in Nanotechnology, I did my master’s in Innovative Medicine. I will start my HTRIC PhD project in September 2023. Our goal is to develop an oxygen-releasing ‘glue’ to prevent postoperative anastomotic leakage and promote wound healing in esophageal cancer patients. This will improve patients’ healthcare and recovery after tumour resection.

This project is applied for by Prof. Dr. Inge S. Zuhorn (UMCG) and Prof. Dr. Ranjita K. Bose (FSE), together with Dr. Jan Willem Haveman (UMCG).

Project start: September 2023 

Early detection of sepsis using reactive oxygen species

PhD candidate Britt Coenen

After finishing my bachelor degree in Life Science I started my master degree in Medical Biology to learn more about key mechanisms in biology and disease. During my PhD on the early detection of sepsis I will apply the knowledge I gained to limit effects from preventable causes, aiming to improve diagnosis and healthcare for patients.

This project is applied for by Prof. Dr. Romana Schirhagl (UMCG), Prof. Dr. Geert van den Boogaart (FSE) and Dr. Hjalmar Bouma (UMCG).

Project start: September 2022

Lower-limb prostheses: optimal human-in-the-loop co-adaptation

PhD candidate Chengxiang Liu

After finishing my Master’s degree in Mechatronic engineering, I worked in institutes developing medical robotics for more than two years. I started my HTRIC PhD project in March 2023. This project aims at developing a human-in-the-loop approach in which the user and the (control settings and mechanical parameters of the) prosthesis co-adapt to each other in an optimization process. The research I do for this project can contribute to  the life quality improvement of amputee patients.

This project is applied for by Prof. Dr. Raffaella Carloni (FSE) and Prof. Dr. Han Houdijk (UMCG).

4D Local drug distribution determination using advanced optical (light sheet) microscopy

PhD candidate Nawal Aledlbi

After doing my bachelor’s in applied chemistry, I went for a master’s degree in analytical chemistry. To broaden my horizon, I joined the Nanoscience TopMaster program at the University of Groningen. During my PhD, I look forward to developing a 4D optical analysis to get an insight into targeted drug distribution, that can lead to efficient personalized medicine in IBD patients using light-sheet microscopy.

This project is applied for by Dr. Pieter van der Zaag (FSE) and Prof. Dr. Wouter Nagengast (UMCG).

Take a breath: Development of a novel lung adhesive sealant for severe COPD patients

PhD candidate Ayla Kwant

After finishing my master’s degree in Biomedical Sciences, I started my HTRIC PhD project in September 2022. The main focus of my research is developing and testing a ‘glue’, which is intended to seal the damaged parts of the lungs of COPD patients and thus improve the capacity of the functional parts. With this research, I hope to contribute to an improved quality of life for COPD patients.

This project is applied for by Prof. Dr. Marleen Kamperman (FSE) and Dr. Simon D. Pouwels (UMCG), together with Prof. Dr. Dirk-Jan Slebos and Prof. Dr. Janette Burgess.