Aline Brouwer

Development of a prognostic test for early interventions in preeclampsia

During my Master’s in Biomedical Sciences, I became fascinated by the immune system. Through my HTRIC PhD project, I am excited to apply this passion and the knowledge I’ve gained to develop a prognostic test for preeclampsia, an inflammatory pregnancy-related condition. This prognostic test will be based on the maternal inflammatory response to paternal Major Histocompatibility Complex molecules expressed by the fetus, which play a central role in fetal rejection during preeclampsia. Identifying women at risk for preeclampsia early on can enable earlier intervention, thereby preventing the development of this condition.

This project is applied for by Dr. Frans Bianchi (FSE) and Dr. Jelmer Prins (UMCG).

Project start: September 2024